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Weight Loss Shots, Now What?

Rebuilding Strength and Metabolism for the Long Run
Introduction

GLP-1 medications like Ozempic, Wegovy, and Mounjaro have gained popularity as weight loss solutions, and while these can serve as effective jumpstarts, the long-term consequences are often overlooked. One side effect, in particular, has the potential for cascading issues down the road: muscle loss.

It’s not breaking news that these medications can lead to a reduction in muscle tissue. For many who are using these medications instead of exercising—specifically, without resistance training—this effect can be even more pronounced. So, what’s the big deal?

Muscle Loss and Metabolism: What’s the Risk?

Muscle loss goes deeper than aesthetics; it directly impacts our overall health, strength, and metabolism:

  1. Metabolic Slowdown: Muscle is a powerhouse for your metabolism, burning calories even at rest. Losing muscle lowers your resting metabolic rate, which not only makes it easier to regain weight but also disrupts glucose regulation, increasing the risk of insulin resistance and metabolic diseases. A healthy metabolism depends heavily on muscle mass.
  2. Strength and Functional Capacity: Beyond body composition, muscle plays a vital role in daily life—from lifting groceries to maintaining stability on uneven ground. With less muscle, physical resilience diminishes, which limits functional independence and increases injury risk as we age. Reduced strength from muscle loss can make once-simple tasks much harder, impacting quality of life.
  3. Health Risks and Aging: Muscle mass is protective against age-related conditions, supporting bone density and lowering the risk of osteoporosis. Importantly, studies show that maintaining muscle can reduce the risk of cognitive decline, including dementia. Preserving muscle is one of the best preventive measures we have for both body and mind.
Step 1: Strength Train—It’s Non-Negotiable

Strength training is essential to regain and build back lost muscle mass, boosting your metabolism:

  • Consistency Matters: Start with 2–3 sessions per week, targeting major muscle groups with compound exercises that build functional strength.
  • Progressive Overload: Gradually increase weights, reps, or sets as you grow stronger. This consistent challenge drives muscle growth and metabolic benefits, helping you reclaim and maintain your strength.
  • Benefit of Having a Coach: Working with a coach provides guidance on proper form, helps prevent injuries, and creates accountability. A coach can personalize your program to fit your needs, adjust it as you progress, and keep you motivated, ensuring you’re getting the most out of each session.
Step 2: Prioritize Protein Intake

After GLP-1 medications, protein intake becomes especially important for muscle recovery. Aim to incorporate a variety of lean protein sources such as chicken, fish, eggs, and plant-based options. Try to consume about 0.7–1 gram of protein per pound of body weight, as higher protein supports muscle repair and satiety. Consistent protein intake fuels recovery, rebuilding muscle mass and metabolic resilience.

Step 3: Balance Strength with Cardio

While cardio supports heart health, too much can counteract muscle growth. At Penance Gym, we implement a strength-focused interval program designed to enhance cardiovascular fitness while actively building muscle tissue and strength.

  • Low-Intensity Cardio: Walking or easy cycling helps with recovery and maintains endurance without excessive muscle breakdown.
  • High-Intensity, Short Sessions: For cardio lovers, short, intense sessions like our strength-focused intervals build endurance without sacrificing muscle gains, offering an ideal blend of strength and cardiovascular health.
Step 4: Embrace Recovery as Part of Training

Recovery is essential for muscle rebuilding:

  • Prioritize Sleep: Aim for 7–9 hours per night to aid muscle repair and hormone regulation.
  • Include Rest Days: Give muscles time to recover between strength training sessions—this is where actual muscle growth happens. Effective recovery is just as important as the effort you put in during training.
Step 5: Stay Consistent and Accountable

Building back muscle and metabolism isn’t a quick fix. Here at Penance Gym, we guide members in creating sustainable fitness routines that align with long-term health goals. If you’ve recently used GLP-1 medications, now’s the time to work on keeping the weight off by building strength, endurance, and a resilient metabolism.

Ready to Take the Next Step?

If you’re ready to rebuild strength and support your metabolism for the long term, we’re here to help. Book a free introductory consultation with us at Penance Gym, and let’s create a plan tailored to your goals. This journey is about building a body you can rely on—now and for years to come.